Search on: 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE 
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Descriptor English:   3',5'-Cyclic-AMP Phosphodiesterases 
Descriptor Spanish:   3',5'-AMP Cíclico Fosfodiesterasas 
Descriptor Portuguese:   3',5'-AMP Cíclico Fosfodiesterases 
Synonyms English:   cAMP Phosphodiesterase
3',5'-Cyclic AMP 5'-Nucleotidohydrolase
3',5'-Cyclic-Nucleotide Phosphodiesterase  
Tree Number:   D08.811.277.352.640.150
D12.644.360.008
D12.776.476.008
Definition English:   Enzymes that catalyze the hydrolysis of CYCLIC AMP to form adenosine 5'-phosphate. The enzymes are widely distributed in animal tissue and control the level of intracellular cyclic AMP. Many specific enzymes classified under this heading demonstrate additional specificity for 3',5'-cyclic IMP and CYCLIC GMP
Indexing Annotation English:   general; prefer specifics; DF: 3 5 CYCL NPD
History Note English:   1994 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   31725 
Unique Identifier:   D015105 

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